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Figure 2 | Molecular Pain

Figure 2

From: The chemerin receptor 23 agonist, chemerin, attenuates monosynaptic C-fibre input to lamina I neurokinin 1 receptor expressing rat spinal cord neurons in inflammatory pain

Figure 2

Chemerin alone does not alter mEPSC frequency in lamina I NK1R+ neurons. A. Representative mEPSC traces recorded prior to (‘baseline’, left) and during chemerin (100 ng/ml) application (right). B. Example cumulative probability curve shows chemerin does not alter the distribution of mEPSC inter-event intervals in an individual neuron (P = 0.992, 2-sample Kolmogorov-Smirnov test). C. Overall, chemerin does not alter mEPSC frequency in non-potentiated conditions (P = 0.824, Wilcoxon, n = 11). Data presented as mean ± SEM, grey points and lines in C indicate trajectories for individual neurons.

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