Channel | Activation | Fast Inactivation | Slow Inactivation | Ramp Current | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | V1/2,act | Slope | n | V1/2,inact | Slope | n | V1/2,inact | Slope | Rin | n | % of Imax | Vpeak | n |
NaV1.7R | 23.1 ± 0.7 | 6.40 ± 0.14 | 40 | 82.5 ± 1.3 | 6.94 ± 0.15 | 15 | -66.0 ± 1.6 | 13.6 ± 0.3 | 0.19 ± 0.02 | 11 | 0.23 ± 0.02 | -42.3 ± 0.9 | 19 |
I136V | 28.8 ± 0.5* | 7.13 ± 0.10* | 43 | 79.7 ± 0.6 | 6.00 ± 0.27* | 13 | -74.0 ± 0.9* | 8.7 ± 0.2* | 0.11 ± 0.01* | 11 | 0.79 ± 0.04* | -48.0 ± 0.5* | 26 |