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Figure 6 | Molecular Pain

Figure 6

From: Differential regulation of morphine antinociceptive effects by endogenous enkephalinergic system in the forebrain of mice

Figure 6

Effect of morphine on the sink current in the ACC evoked by high electrical intensity stimulation. (A) Example of CSD profiles evoked by electrical stimulation (10 mA, 0.5 ms duration and 0.1 Hz) in the hind paw before and after morphine treatment (10 mg/kg) in WT (upper panel) and KO (lower panel) mice. (B) Statistical analysis of the effect of morphine on sink 1, sink 2 and sink 3 in WT and KO mice. Reversibility of the effect was evaluated by treatment with naloxone (0.7 mg/kg). * p < 0.05. ** p < 0.01.

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