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Figure 4 | Molecular Pain

Figure 4

From: The role of TRPV1 in different subtypes of dorsal root ganglion neurons in rat chronic inflammatory nociception induced by complete Freund's adjuvant

Figure 4

Quantification analysis of DRG neurons doubly stained with TRPV1 and neuronal markers. A, B and C show the percentage of TRPV1 positive neurons to NF200-, CGRP-, IB4-positive neurons, respectively. A, In control animals, rare double staining with NF200 was seen; after CFA injection, double staining of TRPV1 with NF200 significantly increased at days 1, 3, 7 and 14. B, Double staining of TRPV1 with CGRP significantly increased in CFA rats from day 1 to day 28. C, In control animals, double staining of TRPV1 with IB4 was ~50%, significantly increased from day 1 to day 14 after CFA injection. D, Area frequency distribution of TRPV1 and NF200 double stained neurons at day 3. After CFA injection, double staining neurons significantly increased in the medium-sized neurons with cell area of 600–1200 μm2. * p < 0.05, ** p < 0.01, *** p < 0.001. n = 3.

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Molecular Pain

ISSN: 1744-8069

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