Figure 3

Selective A1 receptor activation decreases basal and KCl-evoked ATP release. A: Data are presented as mean ± SEM of sample ATP levels from naïve rat DRG in normal perfusate (white bars) and in the continuous presence of NCPA (100 nM, black bars). When DRG are perfused in the presence of NCPA (100 nM) both basal and evoked ATP release is visibly decreased. * denotes p < 0.05 compared with basal ATP levels. B: Summary graph of basal and evoked ATP release in DRG from naive rats with and without NCPA. Data were binned as illustrated in A.