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Figure 1 | Molecular Pain

Figure 1

From: Genetic variation in the serotonin transporter gene (5-HTTLPR, rs25531) influences the analgesic response to the short acting opioid Remifentanil in humans

Figure 1

Average ratings of heat pain intensity (mm VAS) ± SEM during 30 seconds of tonic contact heat stimuli corresponding to 48°Celsius in 43 healthy individuals grouped according to the triallelic 5-HTTLPR genotypes, putative high (n = 12) intermediate (n = 17) and low 5-HTT expression (n = 14). There were no statistically significant differences between the genotype groups in heat pain sensitivity at baseline.

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