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Figure 2 | Molecular Pain

Figure 2

From: Recombinant adeno-associated virus serotype 6 (rAAV2/6)-mediated gene transfer to nociceptive neurons through different routes of delivery

Figure 2

Cell-size profile of eGFP-positive neurons in the L4 DRG following sciatic nerve and intrathecal injection. (A) eGFP-positive neurons classified into small-sized (< 300 μm2, black bars), medium-sized (300-700 μm2, grey bars) and large-sized (>700 μm2, white bars) for the three doses of sciatic nerve injection and the intrathecal injection. Cell-size frequency histogram for eGFP-positive cell population three weeks following sciatic nerve (B) (n = 3, 858 eGFP-positive neurons measured) and intrathecal injection (C) (n = 5, 3146 eGFP-positive neurons measured) of 2.6 × 105 tu rAAV2/6.

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