Skip to main content

Table 1 Properties of mIPSCs in mouse SDH and DDH neurons

From: Different forms of glycine- and GABAA-receptor mediated inhibitory synaptic transmission in mouse superficial and deep dorsal horn neurons

mIPSC properties

 

Channel properties

mIPSC

type

Region

Amplitude

(pA)

Rise time

(ms)

Decay time

(ms)

Frequency

(Hz)

Chargeδ

(pA.ms)

n

Conductance

(pS)

Open probability

(P o )

Channel

number

n

Glycine

SDH

37.1 ± 3.9*

0.85 ± 0.07

8.5 ± 0.8*

0.15 ± 0.03*

364.5 ± 57.7

25

54.3 ± 1.6

.97 ± 0.01

10.3 ± 0.5*

8

 

DDH

64.7 ± 5.0

0.85 ± 0.04

5.5 ± 0.3

0.72 ± 0.13

456.6 ± 39.9

25

55.7 ± 1.8

99 ± 0.01

19.0 ± 5.3

11

GABA A

SDH

25.6 ± 2.4

1.97 ± 0.18*

23.0 ± 3.2*

0.21 ± 0.08

717.3 ± 75.5*

14

22.7 ± 1.7

0.76 ± 0.04*

18.5 ± 1.6*

8

 

DDH

25.3 ± 2.0

1.49 ± 0.10

18.9 ± 1.6

0.18 ± 0.04

486.3 ± 52.4

18

22.4 ± 2.0

0.94 ± 0.02

12.9 ± 1.0

11

  1. * indicates significant differences for SDH and DDH values
  2. δ mIPSC charge calculated in Axograph using averages for peak amplitude, rise- and decay times