TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats

Table 1 Baseline discharge rates of WDR neurons

	Spontaneous (spikes/sec)	10-g von Frey (spikes/sec)	Noxious pinch (spikes/sec)	300-g von Frey (spikes/sec)
Uninjured	1.73 ± 0.38	10.87 ± 4.37	52.80 ± 11.34
CFA-inflamed	4.43 ± 0.79⁺⁺	19.99 ± 3.66*	44.19 ± 9.87
OA	3.93 ± 0.54⁺			27.39 ± 3.83
OA-sham	2.11 ± 0.81			18.04 ± 2.45

significant vs. uninjured group ⁺p < 0.05, and ⁺⁺p < 0.01 (Fisher's LSD), *p < 0.05 (t-test).

ISSN: 1744-8069