From: Nitric oxide is negatively correlated to pain during acute inflammation
Protocol | Microdialysis | Glyceryl trinitrate | Gene Expression | |||||||
---|---|---|---|---|---|---|---|---|---|---|
 | All subjects | Successful sampling |  |  |  |  |  |  | ||
Treatment | Placebo | Ketorolac | Placebo | Ketorolac | Placebo | 100 μg | 150 μg | 200 μg | Placebo | Ketorolac |
Number | 24 | 20 | 19 | 10 | 20 | 18 | 19 | 18 | 15 | 13 |
Age | 20.4 ± 3.9 | 19.0 ± 2.4 | 19.9 ± 3.3 | 20.0 ± 2.7 | 22.9 ± 5.4 | 20.1 ± 3.6 | 22.0 ± 4.9 | 22.4 ± 5.4 | 19.3 ± 3.5 | 18.9 ± 2.8 |
Gender M/F | 7/17 | 5/15 | 3/15 | 1/8 | 15/5 | 12/6 | 9/10 | 9/9 | 8/7 | 8/5 |
Race | Â | |||||||||
White | 18 | 14 | 12 | 6 | 15 | 12 | 13 | 14 | 13 | 10 |
African | 3 | 3 | 3 | 2 | 1 | 4 | 2 | 2 | -- | 2 |
Others | 3 | 3 | 3 | 1 | 4 | 2 | 4 | 2 | 2 | 1 |
Difficulty* | 3.5 ± 0.6 | 3.5 ± .05 | 3.5 ± 0.6 | 3.5 ± 0.5 | 2.95 ± 0.8 | 3.2 ± 0.9 | 3.4 ± 0.8 | 3.3 ± 0.7 | 7.3 ± 0.9 | 7.2 ± 0.9 |
Rescue Medicine | 14 (58%) | 6 (30%) | 11 (61%) | 3 (33%) | N/A | N/A | N/A | N/A | 9 (60%) | 5 (38%) |