Figure 2From: On the possible role of ERK, p38 and CaMKII in the regulation of CGRP expression in morphine-tolerant rats Cumulative dose-response curve of the antinociceptive effects of acute intrathecal injection of morphine in animals previously receiving saline, KN93 (15 nmol), PD98059 (PD, 10 μg), SB203580 (SB, 10 μg), morphine (M) or morphine with KN93 (M/KN93, 15 nmol), PD98059 (M/PD, 10μg) or SB203580 (M/SB, 10μg). Data are expressed as mean ± SEM of 6 animals.Back to article page