Identification and characterization of seven new exon 11-associated splice variants of the rat mu opioid receptor gene, OPRM1

Table 1 Significance values of the semi-quantitative RT-PCR for the expression of the exon 11 associated variants' mRNAs in the selected brain regions

	cb vs hyp	cb vs bs	cb vs hip	cb vs spc	hyp vs bs	hyp vs hip	hyp vs spc	bs vs hip	bs vs spc	hip vs spc
rMOR-1	ns	ns	0.05	0.05	ns	ns	ns	ns	ns	ns
rMOR-1G1	ns	0.001	0.001	0.001	0.001	0.001	0.001	ns	ns	ns
rMOR-1G2	ns	0.001	0.001	0.001	0.001	0.001	0.001	ns	ns	ns
rMOR-1H1	ns	ns	0.01	0.001	ns	0.001	0.001	0.001	0.001	ns
rMOR-1H2	ns	0.01	0.01	0.001	0.01	0.01	0.001	ns	ns	ns
rMOR-1i1	ns	0.001	ns	ns	0.001	ns	ns	0.001	0.001	ns
rMOR-1i2	ns	0.001	ns	ns	0.001	ns	ns	0.00	0.001	ns
rMOR-1i3	ns	0.001	ns	ns	0.001	ns	ns	0.001	0.001	ns

Two-way ANOVA followed by Bonferroni post tests was performed to determine significant difference among the selected brain regions for each variant. cb: cerebellum; hyp: hypothalamus; bs: brainstem; hip: hippocampus; spc: spinal cord; ns: no significance (p > 0.05).

ISSN: 1744-8069