Figure 1From: Satellite glial cell P2Y12 receptor in the trigeminal ganglion is involved in lingual neuropathic pain mechanisms in rats Mechanical allodynia and heat hyperalgesia after LNC. EMG activity recorded from the splenius capitis muscle during mechanical (A) or heat (C) stimulation of the tongue. Time-course changes are shown in mean head-withdrawal reflex threshold to mechanical stimulation of the ipsilateral tongue to in LNC- or sham-rats (B) and head-withdrawal reflex threshold to heat stimulation of the ipsilateral tongue to in LNC- or sham-rats (D). Head-withdrawal reflex threshold is indicated by the arrows in A and C. **: p < 0.01, ***: p < 0.001 (vs. sham-rats; n = 7 in each group, two-way ANOVA with repeated measures, followed by Bonferroni's multiple-comparison tests).Back to article page