| MEDICA16 (10 μM) | GW9508 (30 μM) | ||||
---|---|---|---|---|---|---|
 | Increase | Decrease | No change | Increase | Decrease | No change |
Control | 156.6 ± 25.5 (6/21) | 69.3 ± 4.5***(12/21) | 104.9 ± 1.2 (3/21) | 136.0 ± 15.1 (3/8) | 61.7 ± 9.2 (3/8) | 101.8 ± 6.5 (2/8) |
Carrageenan 6 h | ― (0/8) | 52.6 ± 10.6** (6/8) | 92.9 ± 1.6 (2/8) | ― (0/8) | 56.0 ± 7.7** (7/8) | 109.9 (1/8) |
CFA 3d | 133.3 ± 12.0 (3/15) | 59.1 ± 4.6***(12/15) | ― (0/15) | ― (0/14) | 51.4 ± 6.3***(14/14) | ― (0/14) |
SNL 2–3 w | 113.8 (1/15) | 54.4 ± 6.5***(14/15) | ― (0/15) | ― (0/7) | 53.3 ± 9.8** (7/7) | ― (0/7) |