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Fig. 7 | Molecular Pain

Fig. 7

From: Upregulation of T-type Ca2+ channels in long-term diabetes determines increased excitability of a specific type of capsaicin-insensitive DRG neurons

Fig. 7

Total voltage-gated Na+ current is not significantly changed in the caps−lpH+ neurons of diabetic rats. a A representative example of Na+ currents obtained using a voltage-dependent activation protocol. b Steady-state activation curves of Na+ current in the caps−lpH+ neurons of diabetic and control rats. c Steady-state inactivation curves of Na+ current in the caps−lpH+ neurons of diabetic and control rats. n = 7 from three rats for diabetic and control groups in B and C. Differences in peak current densities were insignificant (p > 0.05). These results clearly demonstrate a lack of Na+ current modulation under diabetic conditions

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