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Figure 1 | Molecular Pain

Figure 1

From: A pain in the ACC

Figure 1

The anatomy of Pavlovian fear. a. Mouse brain sections illustrating key brain regions involved in processing CS information (blue), US information (red) and CS-US associations (purple). b. Simplified schematic of pathways involved in the formation of Pavolvian fear memories. Direct and indirect connections from thalamic nuclei convey information about the CS and US to the amygdala. Tang and colleagues provide evidence that the ACC processes the affective features of painful stimuli, and that pairing a tone with ACC activation can artificially induce Pavlovian fear memories. Abbreviations: ACC, anterior cingulate cortex; Au, primary auditory cortex; Amy, amygdala; Pr, perirhinal cortex; S1, primary somatosensory cortex.

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