Figure 3From: Physical interaction and functional coupling between ACDP4 and the intracellular ion chaperone COX11, an implication of the role of ACDP4 in essential metal ion transport and homeostasis Killing curve of HEK293 cells for selected divalent ions A. Killing curves for Cu2+, Mn2+, Co2+ and Zn2+. B. Killing curve for Mg2+. Cell death was estimated by counting a total of 300 cells in each field with 2–3 fields under microscope. Apparent EC50 values were 0.9 mM for Cu2+, 1.4 mM for Mn2+, 0.8 mM for Co2+, 0.6 mM for Zn2+ and 64 mM for Mg2+.Back to article page