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Figure 4 | Molecular Pain

Figure 4

From: Physical interaction and functional coupling between ACDP4 and the intracellular ion chaperone COX11, an implication of the role of ACDP4 in essential metal ion transport and homeostasis

Figure 4

The effects of ectopic expression of ACDP4 on metal ion toxicity in HEK293 cells. ACDP4 is ectopically expressed in HEK293 cells using pcDNA3.1-ACDP4 plasmid transfection. Transfection of an empty vector (pcDNA3.1) was used as a control. Cells were cultured for 48 hrs in medium containing the 5 type of metal ions, and each type of metal ions was at its concentration of the apparent EC50 established in Figure 3. For normalization, the viability of control cells was scaled to 100%, and cell viabilities for cells transfected with ACDP4 were normalized in reference to the control cells. Data represent mean ± SEM, * P < 0.05, Student-t test.

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Molecular Pain

ISSN: 1744-8069

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