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Figure 6 | Molecular Pain

Figure 6

From: Physical interaction and functional coupling between ACDP4 and the intracellular ion chaperone COX11, an implication of the role of ACDP4 in essential metal ion transport and homeostasis

Figure 6

A postulated model of ACDP-mediated metal ion delivery in mammalian cells. An essential metal ion is first transferred through plasma membrane via an ACDP. An intracellular chaperone specifically interacts with the intracellular parts of ACDP. The chaperone receives the metal ion from ACDP and then carries the ion to a specific target protein. Overload of cells with essential metals results in oxidative cell death.

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