| Slope (mV/ms) | 1/2 width (ms) | Decay time (ms) |
---|
control | 1.8 ± 0.4 | 14.5 ± 2.6 | 13.2 ± 2.8 |
propofol | 1.6 ± 0.4 | 6.3 ± 0.4** | 16.3 ± 3.2* |
+ bicuculline | 1.9 ± 0.5 | 13.5 ± 2.1 | 12.2 ± 2.4 |
- EPSPs are evoked by extracellular stimulation of corticothalamic fibers (a train of 5 pulses, 0.15 ms, 33 Hz). Data are derived from experiments as described in Fig. 2. Slope (dv/dt) representing depolarization rate is measured from the rising phase (20–80%) of the first EPSP. 1/2 width is measured at 50% of peak amplitude; decay time (20–80%) representing repolarization rate is measured from the falling phase of the fifth EPSP. *, P < 0.05. **, P < 0.001, vs. control.