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Table 1 Evidence for the pro-nociceptive effects of ACC

From: Central inhibition and placebo analgesia

ACC manipulation

Nociceptive (+)/analgesia (-)

Anatomic lesions in the ACC

-

Electrical stimulation locally in the ACC

+

Chemical activation within the ACC

+

Opioid injection in the ACC

-

Electrophysiological recordings from the ACC

+

Imaging data

+/-