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Table 3 Genes with significant adult inflammation-induced alterations in their expressions in the left LDH (ipsilateral to the CFA-inflamed neonatally-injured hindpaw) in CAR-P3 rats as compared to those in the left LDH of CONT and CAR-P12 animals after inflammation of the corresponding paw [one-way ANOVAs, (with the Benjamini and Hochberg's FDR correction procedure set at the P-value cutoff of 0.05) followed by Tukey's post-hoc tests (with the same P-cutoff value) in the implementation of GeneSpring GX software (Agilent, Palo Alto, CA).)]. Differences in gene expression are presented as ratios between CAR-P3 and CONT, CAR-P12 and CONT, and CAR-P3 and CAR-P12 groups. Statistically insignificant differences are marked as 'ND' The comparisons are based on the microarray profiling that employed 5 slides for comparison of CONT and CAR-P3 samples and another 5 slides for comparison of CONT and CAR-P12 samples.

From: Neonatal local noxious insult affects gene expression in the spinal dorsal horn of adult rats

Left LDH (ipsilateral to the site of neonatal injury)
Genes CAR-P3/CONT CAR-P12/CONT CAR-P3/CAR-P12 Genes CAR-P3/CONT CAR-P12/CONT CAR-P3/CAR-P12
5-HT1a 3.3 ND 2.4 GABAAα2 2.0 ND 2.0
5-HT1d 1.9 ND 2.1 GABAAα4 1.8 ND 2.0
5-HT1e 1.6 ND 1.6 GABAAα5 1.9 1.4 1.4
5-HT1f 1.8 ND 2.0 GABAAα6 2.9 1.7 1.7
5-HT2c 1.4 ND 1.7 GABAB1b 2.6 ND 2.4
5-HT4 1.9 ND 2.4 GABAB1c 2.2 1.5 1.5
5-HT5a 3.0 ND 2.3 NR1-1b 3.2 2.4 1.3
5-HT5b 3.1 2.1 1.5 NR1-4a 2.2 ND 2.0
5-HT6 1.7 ND 1.7 NR2A 2.1 1.5 1.4
IL-1α 1.6 ND 1.6 NR2D 2.3 1.5 1.5
IL-5 2.5 1.6 1.6 NR3B 1.6 ND 2.0
IL-6 1.8 ND 2.2 GluRD 2.0 ND 2.0
IL-12A 1.7 ND 1.3 GluR6 2.1 ND 1.7
IL-12R β1 6.1 ND 4.3 mGluR1a 2.5 1.4 1.8
IL-15 2.4 ND 2.0 CGRPR 2.6 1.5 2.4
IL-20 3.4 ND 2.4 NT-4 2.0 1.2 1.6
IL-24 3.5 ND 3.0 CALK2 2.5 ND 1.9
TrkA 2.3 ND 2.0 VGF 2.6 ND 1.4
TrkC 1.5 ND 1.4 NK2 1.5 2.2 0.7