Table 2 Comparison of the activation and deactivation kinetics of TRPV1. Mean activation and deactivation rates of responses from TRPV1 expressing HEK-293 cells following application of capsaicin (1 μM), acidic pH (5.5) or the combination. Row 3 represents activation and deactivation rates of currents evoked by 1 μM capsaicin following pre-exposure to acidic conditions (pH 5.5). Row 4 represents the activation rates of acid-evoked currents following pre-exposure to capsaicin (1 μM). The absolute value of rate measurements had slight day-to-day variations (possibly due to relative position of the drug application tube). Therefore values in this table are from cells in which direct comparisons can be made. Values are mean ± S.E.M.