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Figure 6 | Molecular Pain

Figure 6

From: A P2X receptor-mediated nociceptive afferent pathway to lamina I of the spinal cord

Figure 6

Block of αβmeATP-induced suppression of eEPSCs by PPADS A. The three traces on the top, middle and bottom panels show eEPSCs recorded from a lamina I neuron in normal bath solution (Control), during the application of 100 μM αβmeATP and after washout of αβmeATP (Recover), respectively. B. The same neuron shown A was tested again in the presence of 10 μM PPADS. In both A and B, a trace of eEPSC was obtained from an average of eEPSCs evoked by 10 sweeps of stimuli. C. Pooled results (n = 4) show effects of 100 μM αβmeATP on eEPSC amplitude in the absence and presence of 10 μM PPADS. Data represent percent of control values, and eEPSCs in control is scaled as 100%.

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