Figure 3
From: Pavlovian fear memory induced by activation in the anterior cingulate cortex
Activation of metabotropic glutamate receptors in the ACC caused long-term fear memory. (a) ACC tACPD microinjection (0.25 μg in 0.5 μl; indicated by an arrow) was paired with a tone (indicated by filled bar) on the conditioning day; (b, c) Percentage freezing to the tone (b) and the conditioning context (c) measured at 1 day and 3 days after paired training (n = 5 mice). *P < 0.05 compared with the control. (d) The sites in the ACC for tACPD microinjection on the schematic representation of coronal section 0.62 mm anterior to the Bregma.