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Figure 3 | Molecular Pain

Figure 3

From: ARA 290, a peptide derived from the tertiary structure of erythropoietin, produces long-term relief of neuropathic pain coupled with suppression of the spinal microglia response

Figure 3

Effect of ARA 290 on Iba-1 immunoreactivity in the L5 spinal cord segment of animals 2 weeks after spared nerve injury. Representative photomicrographs of Iba-1 immunoreactivity (green) in the L5 spinal cord segment of animals 2 weeks after spared nerve injury (SNI). (A-C) Low power magnifications, (D-F) detailed images of (A-C) as indicated by the white rectangles, and (G-I) high power magnifications of the spinal cord of animals that underwent: A, D and G. SNI and vehicle treatment, B, E and H. SNI and treatment with 30 μg/kg ARA 290, C, F and I. sham surgery without treatment. The left-hand side of the photomicrographs represents the ipsilateral side of the animal, innervating the site of spared nerve injury.

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Molecular Pain

ISSN: 1744-8069

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