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Figure 8 | Molecular Pain

Figure 8

From: Activation of peripheral KCNQ channels attenuates inflammatory pain

Figure 8

Analgesic effect of intraplantar administration of retigabine and ICA-27243. Nociceptive behavior was induced by an intraplantar injection of formalin. Ten min prior to the formalin injection, 100 and 300 μg retigabine and ICA-27243 was injected into intraplantar surface of the ipsilateral paw (A & C), respectively and of the contralateral paw (B & D), respectively. The duration of licking behavior was recorded 0–10 min (1st phase) and 10–30 min post-formalin injection (2nd phase). Each data was presented as the mean ± S.E.M. in 6 rats. *p < 0.05.

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