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Table 3 Changes in transcriptional level of Na v s in injured (L5) and non-injured (L4) DRG after SNL

From: Voltage-gated sodium channel expression in mouse DRG after SNI leads to re-evaluation of projections of injured fibers

 

% of modification (SNL/sham)

p-values of treatment (SNL) for each DRG

Overall p-value of treatment (SNL)

DRGs

L5

L4

L5

L4

 

Nav1.1

-61%

-33%

**

*

p < 0.001

Nav1.2

-19%

-36%

ns

ns

p = 0.013

Nav1.3

+14%

-23%

ns

ns

p = 0.923

Nav1.6

-63%

-18%

**

ns

p = 0.004

Nav1.7

-53%

-15%

*

ns

p = 0.015

Nav1.8

-74%

+8%

***

ns

p = 0.003

Nav1.9

-78%

-17%

***

ns

p = 0.002

  1. % of change of Navs transcript in SNL as compared to sham in injured L5 and non-injured L4 DRG. 2–way ANOVA with independent measures to test for overall treatment effect and post hoc Bonferroni to test for statistical significance of treatment in each DRG (*p < 0.05, **p < 0.01 and ***p < 0.001).