The effect of acupuncture needle combination on central pain processing-an fMRI study

Molecular Pain

Table 1 Regional of activities extracted from EA2>baseline (P<0.01, clutster >150 voxels); SSC2: secondary somatosensory cortex

Hemisphere	Region of activity	T-value	Cluster size	Brodmann area	Peak coordinates	P-value
Left hemisphere	*Sensory/Discriminatory*
	SSC2	−12.529	299421	7	−31, -50, 45	<10⁻⁶
	*Affective & Emotional*
	Insular cortex	−6.809	860	13	−40, 1, 9	0.000029
	Hippocampus	−5.4712	1670	N/A	−28, -11, -21	0.000194
	*Response & Neuromodulatory*
	Prefrontal cortex	−8.904	13870	9	−25, 52, 30	0.000002
	Prefrontal cortex	−6.004	308	11	−31, 28, -24	0.000089
	Prefrontal cortex	−4.462	283	10	−4, 67, 18	0.00096
	Frontal cortex	−4.265	352	8	−19, 28, 48	0.001332
	Brainstem/Pons	−3.993	274	N/A	−7, -26, -39	0.002112
	Frontal operculum	−3.953	477	44	−49, 13, 12	0.002263
	Prefrontal cortex	−3.930	189	10	−7, 61, -3	0.002353
Right hemisphere	*Sensory/Discriminatory*
	Parietal	−5.089	405	38	50, 25, -24	0.00035
	Parietal	−4.723	169	38	56, 10, -12	0.000627
	Parietal	−4.597	242	38	29, 22, -27	0.000769
	Parietal	−4.579	154	38	41, 16, -9	0.000792
	*Affective & Emotional*
	Insula cortex	−4.170	529	13	35, 13, -3	0.001563
	*Response & Neuromodulatory*
	Frontal cortex	−8.442	4409	8	26, 16, 36	0.000004
	Cerebellum	−5.831	589	Cerebellum	23, -29, -30	0.000114
	Post. cerebellum	−5.097	286	Claustrum	35, -14, 12	0.000346
	Frontal operculum	−4.680	1369	45	44, 22, 12	0.000671
	Premotor cortex	−4.033	201	6	8, 31, 54	0.001971

ISSN: 1744-8069