Figure 1

Neck muscle inflammation activates upper-cervical dorsal horn neurons. A. Representative image of a transverse spinal cord section (C2 level) from a carrageenan-injected animal showing cFos labelling in the ipsilateral dorsal horn. Note, labelled neurons are concentrated in the superficial dorsal horn with a lateral bias. B. Maps showing group data from carrageenan-injected animals. The location of cFos labelled neurons have been collapsed onto standardised C1 and C2 templates (adapted from [13]). C. Graph comparing mean number of cFos positive neurons in control, sham, and carrageenan-injected animals. Data are separated into ipsilateral and contralateral staining across spinal levels C1 and C2.