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Figure 1 | Molecular Pain

Figure 1

From: Prophylactic cannabinoid administration blocks the development of paclitaxel-induced neuropathic nociception during analgesic treatment and following cessation of drug delivery

Figure 1

Paclitaxel induces mechanical allodynia without producing hypersensitivity to heat. a. Paclitaxel treatment produced transient heat hypoalgesia but no long-term changes in paw withdrawal latencies to heat whereas b. the same animals developed mechanical allodynia. Inj indicates days when injections of paclitaxel or cremophor vehicle occurred. Taxol; paclitaxel. *P < 0.05, **P <0.01 vs. Cremophor Vehicle, (ANOVA). N = 6 per group.

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