Figure 1From: Prophylactic cannabinoid administration blocks the development of paclitaxel-induced neuropathic nociception during analgesic treatment and following cessation of drug delivery Paclitaxel induces mechanical allodynia without producing hypersensitivity to heat. a. Paclitaxel treatment produced transient heat hypoalgesia but no long-term changes in paw withdrawal latencies to heat whereas b. the same animals developed mechanical allodynia. Inj indicates days when injections of paclitaxel or cremophor vehicle occurred. Taxol; paclitaxel. *P < 0.05, **P <0.01 vs. Cremophor Vehicle, (ANOVA). N = 6 per group.Back to article page