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Figure 1 | Molecular Pain

Figure 1

From: Artemin growth factor increases nicotinic cholinergic receptor subunit expression and activity in nociceptive sensory neurons

Figure 1

Immunolabeling shows nAChRα3 is expressed in GFRα3-neurons. Labeling of nAChRα3-positive neurons in ART-OE ganglia (A-C) is more intense compared to WT ganglia (D-F). Quantitative analysis showed the percentage of GFRα3 neurons that express nAChRα3 is greater in ganglia of ART-OE mice (46%) compared to WT mice (9.7%) (p < 0.05%, Student’s t test). Arrows indicate GFRα3/nAChRα3 positive neurons; asterisks mark nAChRα3 neurons that are not GFRα3 positive; arrowhead shows GFRα3 neuron that is nAChRα3 negative.

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