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Figure 4 | Molecular Pain

Figure 4

From: Nasal application of neuropeptide S inhibits arthritis pain-related behaviors through an action in the amygdala

Figure 4

NPS effects on anxiety-like behavior but not locomotor activity. (A, B) Open-arm choice during the initial 5 min in the elevated plus-maze (see Methods) was measured in normal (A) and arthritic rats (B) 30 min after nasal application of saline (Sal; n = 6 normal rats; n = 6 arthritic rats) or NPS (14 nmol; n = 6 normal rats; n = 6 arthritic rats). NPS increased open-arm choice in arthritic animals significantly. * P < 0.05, unpaired t-test. (C, D) Locomotor activity was measured in the same groups of normal (C) and arthritic (D) rats as the total number of beam crossing into the 4 arms during 15 min. NPS had no significant effect (unpaired t-test).

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