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Figure 5 | Molecular Pain

Figure 5

From: Postsynaptic potentiation of corticospinal projecting neurons in the anterior cingulate cortex after nerve injury

Figure 5

Nerve injury increased the AMPAR mediated postsynaptic responses in the ACC. A, Schematic figures showing the recording on layer V by stimulating shallow layers (II/III), plus one biocytin labeled layer V pyramidal cell. B, The input–output curve of ACC layer V neurons became steeper in mice with nerve injury, compared with mice with sham injury. Two-way ANOVA followed by Tukey’s post hoc test; C, An inward rectification of AMPA I-V curve of layer V neurons after nerve injury. D-E, The frequency of the mEPSC (D) and the paired-pulse ratio (E) is not changed after nerve injury.

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