Figure 2From: Descending controls modulate inflammatory joint pain and regulate CXC chemokine and iNOS expression in the dorsal horn Immunohistochemistry confirms depletion of 5-HT fibres by 5,7-DHT treatment. Representative images indicate that 5,7-DHT treatment leads to a complete loss of 5-HT punctate immunoreactivity within the dorsal horn. Top row x 5 magnification, scale bar indicates 400Â ÎĽm, bottom row x 10 magnification, scale bar indicates 200Â ÎĽm. Tissue was taken at 7d post CFA injection (13d following 5,7-DHT depletion).Back to article page