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Figure 5 | Molecular Pain

Figure 5

From: Roles of ASIC3, TRPV1, and NaV1.8 in the transition from acute to chronic pain in a mouse model of fibromyalgia

Figure 5

Expression of Na V 1.8 and isolectin B4 (IB4) in muscle afferent DRG neurons labeled with retrograde tracing of flourogold in Na V 1.8+/− -Cre mice carrying the CAG-STOPfloxed -EGFP allele. (A) NaV1.8-positive, IB4-negative neurons represented 11.5% of total muscle afferent DRG neurons. (B) NaV1.8-negtive, IB4-positive neurons represented 4.7% of total muscle afferent DRG neurons. (C) NaV1.8-positive, IB4-positive neurons represented 20.0% total muscle afferent DRG neurons. (D) NaV1.8-negative, IB4-negative neurons represented 63.7% of total muscle afferent DRG neurons. Arrows indicate the neurons of the cell type described at the right panel.

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