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Table 1 Effect of acid-sensing ion channel 3 (ASIC3) and transient receptor potential cation channel V1 (TRPV1) inhibition on maintenance of hyperalgesia induced by dual acid injections

From: Roles of ASIC3, TRPV1, and NaV1.8 in the transition from acute to chronic pain in a mouse model of fibromyalgia

First injection Maintenance of hyperalgesia induced by the second acid injection on
  Day 1 Day 2 Day 5
Acid with APETx2 7 days (20 pmole) 6 days (20 pmole) 4 hr (20 pmole)
3 days (200 pmole)
Acid with capsazepine 9 days 9 days 7 days
Acid with vehicle >12 days >12 days >12 days