Figure 2
From: Anoctamin 1 contributes to inflammatory and nerve-injury induced hypersensitivity
Ablation of ANO1 in DRG neurons attenuates bradykinin and formalin induced nociception. (A) Nocifensive behaviors were counted for 30 min after bradykinin (1 μg, 50 μl) was injected to left hind paws of Adv/Ano1fl/fl and its control mice (*p < 0.05, n = 8). (B) Nocifensive behaviors were counted for 45 min after formalin (5%, 50 μl) was injected to left hind paws of Adv/Ano1fl/fl and its control mice (*p < 0.05, n = 6–7). Phase I represents measurement for the first 15 min while phase II represents measurement for 15 ~ 45 min.