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Figure 6 | Molecular Pain

Figure 6

From: β-arrestin-2-biased agonism of delta opioid receptors sensitizes transient receptor potential vanilloid type 1 (TRPV1) in primary sensory neurons

Figure 6

Acutely administered SNC80 and ARM390 are equally effective at blocking thermal allodynia in rats. Following baseline thermal testing separate groups of rats received intraplantar bradykinin (25 μg) 15 minutes before co-injection of prostaglandin E2 (300 ng) and SNC80 (20 μg), ARM390 (20 μg), or vehicle (4% DMSO, 2% Tween20, PBS). Paw withdrawal latency was measured after 20 min, and data are expressed as the mean ± SEM change from individual pre-injection baseline response for each animal. n = 6 rats per group. *, p > 0.05 by one-way ANOVA.

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Molecular Pain

ISSN: 1744-8069

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