Skip to main content
Figure 3 | Molecular Pain

Figure 3

From: Involvement of the chemokine CCL3 and the purinoceptor P2X7 in the spinal cord in paclitaxel-induced mechanical allodynia

Figure 3

A CCL3-neutralizing antibody suppresses the development and maintenance of paclitaxel-induced mechanical allodynia. Intrathecal administration of a CCL3-neutralizing antibody (4 ng/10 μL) or control IgG2A was done once a day for 7 days (from a day before the first paclitaxel injection until day 6) (A) or once on day 7 after the first paclitaxel injection (B) (n = 6, *P < 0.05, **P < 0.01, ***P < 0.001, vs. control group). Values are means ± s.e.m.

Back to article page