Figure 6From: Optimization of a cisplatin model of chemotherapy-induced peripheral neuropathy in mice: use of vitamin C and sodium bicarbonate pretreatments to reduce nephrotoxicity and improve animal health status Long term assessment of kidney functions in control/saline, saline/cisplatin or vitamin C/cisplatin groups. Creatinine (A), ketone (B) and glucose (C) levels as well as blood pH (D), urine pH (E) and kidney weight ratios (F) were similar in control/saline, saline/cisplatin or vitamin C/cisplatin groups 60 days after the last cisplatin injection. Data are expressed as mean ± s.e.m. (n = 6–8 per group).Back to article page