Figure 1From: Spatial and temporal pattern of changes in the number of GAD65-immunoreactive inhibitory terminals in the rat superficial dorsal horn following peripheral nerve injury Behavioural changes following application of the cuff. Results for the ipsilateral hindpaws are shown for both neuropathic (n = 10) and sham-operated (n = 10) Wistar rats while the contralateral values are shown for neuropathic rats only. Each point represents the mean ± SEM as a percentage of sham values (percentage of sham ipsilateral hindpaw for neuropathic ipsilateral results and percentage of sham contralateral hindpaw for neuropathic contralateral results). A) 50% withdrawal threshold to von Frey hairs in neuropathic and sham-operated rats as a percentage of sham values obtained with the up-down method. B) Assessment of thermal hyperalgesia using the Hargreaves’ test. Withdrawal threshold to light stimulus as a percentage of sham values. In A and B, comparison to sham ipsilateral hindpaw *P < 0.05, **P < 0.01 by 2 way ANOVA with Bonferroni correction. Comparison to contralateral hindpaw of cuff animals #P < 0.05, ##P < 0.01.Back to article page