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Figure 3 | Molecular Pain

Figure 3

From: Transient receptor potential ankyrin 1 in spinal cord dorsal horn is involved in neuropathic pain in nerve root constriction rats

Figure 3

HC-030031 decreases the frequencies and amplitudes of spontaneous EPSCs. Representative traces from in vivo patch-clamp recording show the spontaneous EPSCs in the absence (left) or presence (right) of HC-030031 (100 μM) of spontaneous EPSCs (A), air-evoked EPSCs (B), and pinch-evoked EPSCs (C). The frequencies and amplitudes of spontaneous EPSCs were significantly higher in the root constriction (RC) rats than in the sham rats and naïve rats. The frequencies and amplitudes were significantly decreased after HC-030031 treatment in all groups of rats.

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