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Figure 4 | Molecular Pain

Figure 4

From: The prophylactic effects of a traditional Japanese medicine, goshajinkigan, on paclitaxel-induced peripheral neuropathy and its mechanism of action

Figure 4

Comparison of protein expression of TRPV4 in the dorsal root ganglions. A. Comparison of the expression of TRPV4 by Western blot. Expression of TRPV4 was significantly increased in the PTX group and significantly suppressed by the co-administration of GJG. The experiment was repeated 3 times, and the means were expressed numerically. The figures shown are representative photographs. †P < 0.05, vs. control. ‡P < 0.01, vs. PTX + GJG. B. Comparison of the expression of TRPV4 by immunohistochemistry. The expression of TRPV4 in ganglion cell was classified into negative, weakly positive, and strongly positive, as shown in the figure and the level of TRPV4 expression between the 3 groups was compared. *P < 0.005, **P < 0.01.

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Molecular Pain

ISSN: 1744-8069

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