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Figure 4 | Molecular Pain

Figure 4

From: Gabapentin reverses central hypersensitivity and suppresses medial prefrontal cortical glucose metabolism in rats with neuropathic pain

Figure 4

Functional connectivity in the brain of pre-SNI, post-SNI and GBP-treated conditions. (A) Interregional correlation matrices of the 3 conditions of SNI rats. Pearson’s correlation coefficients were color-coded. The warm and cold color scales stand for positive and negative significant correlations, respectively. Note the strong positive connections were appeared in the (B) basal ganglia to limbic cortex, (C) basal ganglia to thalamus, and (D) thalamus to limbic cortex. The enlarged rectangles in (B) to (D) represent the detail of correlation matrices boxed in A. SNI rats, n = 12.

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