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Figure 4 | Molecular Pain

Figure 4

From: Adenylyl cyclase subtype 1 is essential for late-phase long term potentiation and spatial propagation of synaptic responses in the anterior cingulate cortex of adult mice

Figure 4

Effect of NB001 and gabapentin on the spatial distribution induced by TBS. (A-B) Polygonal diagrams of showed the baseline areas of the activated sites with fEPSPs (blue) and the enlarged areas after TBS (red) (n = 6 slices/6 mice). Overlapped blue or red regions indicated the high frequently activated areas. (C-D) Baseline areas of activated sites with fEPSPs (blue) was not enlarged after TBS (red) in the presence of NB001 (0.1 μM) (n = 6 slices/6 mice). (E-F) Baseline areas of activated sites with fEPSPs (blue) and the enlarged areas after TBS (red) with gabapentin (100 μM) application (n = 6 slices/6 mice). (G-H) Summarize number of active channels (G) and areas (H) that are activated before and after TBS induction.

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Molecular Pain

ISSN: 1744-8069

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