Figure 1From: Cannabinoid receptor 2 agonist attenuates pain related behavior in rats with chronic alcohol/high fat diet induced pancreatitis AHF diet induced chronic pancreatitis pathology and protection by LY3038404 HCl. Representative bright field images of pancreatic paraffin sections stained with H & E. A. Normal chow fed rats had normal pancreatic architecture with evenly distributed acini and islets of Langerhans. B. Rats with AHF diet chronic pancreatitis had abnormal pancreatic tissue architecture including global degeneration (with blurred cell borders) and multiple vacuolization sites due to fat deposition. C. LY3038404 HCl treated rats with AHF pancreatitis showed improvement of tissue damage. D. The histogram shows the histological severity rating scores (HHS) of different treatment groups. The score is a total of the different parameters for each animal averaged within each group, expressed as a median (One-way ANOVA, Kruskal-Wallis, *p < 0.05).Back to article page