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Figure 8 | Molecular Pain

Figure 8

From: A comparison of RNA-seq and exon arrays for whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat

Figure 8

Functional analysis of differentially expressed genes after SNT as determined by RNA-seq (50 M) and exon arrays. A) Distribution of DE genes according to respective protein classes is similar for both datasets. B) Top Biological Functions/“Diseases and Disorders” assigned to DE genes largely overlap between the two datasets. Ci, Cii) Statistically overrepresented “canonical pathways” rank differently between the datasets, with top pathways in exon arrays being mostly related to immune function (Ci), while in RNA-seq, neuronal pathways are more represented (Cii).

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Molecular Pain

ISSN: 1744-8069

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