Table 1 Allelic frequencies of SNPs in five LD blocks around the P2RX7 gene of Japanese subjects
rs number of SNPs | Position | Â | Major allele | Minor allele | Frequency | LD block |
|---|---|---|---|---|---|---|
rs12819523 | Flanking_5UTR | -45261 | G | A | 7.5% | Â |
rs12819930 | Flanking_5UTR | -45087 | G | A | 10.7% | 1 |
rs10492051 | Flanking_5UTR | -45012 | G | - | 0.0% | Â |
*rs2708092 | Flanking_5UTR | -44792 | A | G | 49.0% | 1 |
*rs1180012 | Flanking_5UTR | -40230 | C | T | 38.8% | 1 |
rs2516210 | Flanking_5UTR | -35256 | T | C | 15.9% | 1 |
rs1796421 | Flanking_5UTR | -30332 | T | C | 15.9% | 1 |
rs1796412 | Flanking_5UTR | -28966 | T | C | 18.2% | 1 |
rs7298521 | Flanking_5UTR | -28847 | C | T | 22.9% | 1 |
rs1794899 | Flanking_5UTR | -27705 | G | A | 18.0% | 1 |
rs1796415 | Flanking_5UTR | -27667 | T | - | 0.0% | Â |
rs3892756 | Flanking_5UTR | -16010 | T | - | 0.0% | Â |
rs10849846 | Flanking_5UTR | -12255 | T | C | 21.8% | 1 |
rs208277 | Flanking_5UTR | -10097 | A | G | 41.1% | 1 |
rs12314721 | Flanking_5UTR | -4921 | C | T | 14.9% | 1 |
rs9805004 | Flanking_5UTR | -4808 | C | T | 18.2% | 1 |
rs670541 | Flanking_5UTR | -1044 | C | T | 8.9% | 1 |
rs591874 | Intron1 | IVS1 + 567 | A | C | 40.9% | 1 |
rs7959194 | Intron1 | IVS1 + 5089 | G | - | 0.0% |  |
rs11065450 | Intron1 | IVS1 + 8759 | C | A | 28.7% |  |
rs568531 | Intron1 | IVS1 + 8775 | C | T | 7.5% | 2 |
rs607094 | Intron1 | IVS1 + 9566 | T | C | 6.4% | 2 |
rs208286 | Intron1 | IVS1-5688 | G | - | 0.0% | Â |
rs17525809 | Exon2 | T227C[V76A] | T | C | 8.9% | Â |
*rs1718125 | Intron2 | IVS2 + 263 | G | A | 28.3% | 3 |
rs10849851 | Intron3 | IVS3-2061 | A | G | 21.0% | 3 |
rs1653583 | Intron3 | IVS3-53 | C | T | 7.2% | 3 |
*rs208293 | Intron4 | IVS4-47 | G | A | 41.1% | 3 |
rs208294 | Exon5 | T463C[Y155H] | T | C | 43.5% | 3 |
rs1186055 | Intron5 | IVS5 + 206 | G | T | 39.5% |  |
rs208296 | Intron5 | IVS5 + 630 | C | T | 36.1% |  |
rs11065464 | Intron5 | IVS5-1025 | C | A | 24.3% | Â |
rs208298 | Intron5 | IVS5-922 | G | A | 16.6% | 4 |
rs654856 | Intron5 | IVS5-38 | C | A | 13.4% | 4 |
rs2857589 | Intron7 | IVS7 + 486 | C | A | 5.1% | 4 |
rs503720 | Intron7 | IVS7-217 | G | A | 16.1% | 4 |
rs16950860 | Exon8 | C808T[R270C] | C | - | 0.0% | Â |
rs7958311 | Exon8 | G809A[R270H] | G | A | 35.6% | Â |
rs7958316 | Exon8 | G827A[R276H] | G | - | 0.0% | Â |
*rs1718136 | Intron8 | IVS8-3583 | A | G | 15.0% | 5 |
rs7137542 | Intron8 | IVS8-545 | G | - | 0.0% | Â |
*rs7132846 | Intron9 | IVS9-16 | C | T | 12.9% | 5 |
rs1718119 | Exon11 | G1040A[A348T] | G | A | 17.5% | 5 |
rs1653598 | Intron11 | IVS11 + 34 | A | G | 14.9% | 5 |
rs2567998 | Intron11 | IVS11-16 | A | - | 0.0% | Â |
rs10160951 | Exon12 | C1289G[P430R] | C | - | 0.0% | Â |
rs12829218 | Intron12 | IVS12 + 133 | A | - | 0.0% |  |
rs891781 | Intron12 | IVS12 + 180 | C | T | 17.5% | 5 |
rs7312642 | Intron12 | IVS12-1921 | G | T | 12.1% | Â |
rs12815078 | Intron12 | IVS12-101 | A | G | 6.1% | Â |
rs2230912 | Exon13 | A1379G[Q460R] | A | - | 0.0% | Â |
rs3751144 | Exon13 | C1422T | C | T | 12.9% | Â |
rs3751143 | Exon13 | A1487C[E496A] | A | C | 32.0% | Â |
rs1718161 | Flanking_3UTR | +3582 | A | G | 6.5% | Â |
rs2686365 | Flanking_3UTR | +9907 | C | - | 0.0% | Â |