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Figure 6 | Molecular Pain

Figure 6

From: Impaired neuropathic pain and preserved acute pain in rats overexpressing voltage-gated potassium channel subunit Kv1.2 in primary afferent neurons

Figure 6

Overexpressing Kv1.2 in the DRG does not alter capsaicin-induced acute nociceptive pain. (A) The duration of capsaicin-induced paw licking/lifting was recorded for 5 minutes after capsaicin injection in the AAV5-EGFP-injected and AAV5-Kv1.2-injected groups. nā€‰=ā€‰5/group. (B-D) Paw withdrawal responses of AAV5-EGFP-injected and AAV5-Kv1.2-injected rats to mechanical (B), heat (C), and cold (D) stimuli on the ipsilateral side prior to viral injection (baseline), before capsaicin injection (Pre-Cap; 5 weeks after viral injection), and 30 minutes after capsaicin injection (Post-Cap). nā€‰=ā€‰5/group.

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